BH3-dependent and independent activation of BAX and BAK in mitochondrial apoptosis - ScienceDirect
MoldoveanuLab on Twitter: "We show how BAK undergoes direct activation by BH3-only Initiators (e.g. the BCL-2 protein BID) and autoactivation (active BAK activates dormant BAK), which share a common 'hit-and-run' structural basis
Discovery of Small Molecule Bak Activator for Lung Cancer Therapy
Robust autoactivation for apoptosis by BAK but not BAX highlights BAK as an important therapeutic target | Cell Death & Disease
Protein Bak - an overview | ScienceDirect Topics
BCL‐2‐family protein tBID can act as a BAX‐like effector of apoptosis | The EMBO Journal
The anti-apoptotic protein MCL1, a novel target of lung cancer therapy